Our foundational daily serving of 300mg, known to boost and sustain NAD+ levels to over 50% in most individuals with daily use. Support your cellular energy production and support cellular repair with Niagen®, our award-winning, superior NAD+ precursor.
Tru Niagen is one of the most well-researched NAD+-boosting supplements available. Supports resilience against daily stressors and the natural aging process at the cellular level. Increase your NAD+ levels to support heart, brain, muscle, and whole-body health for enhanced vitality and healthy aging.
- Adults can take one capsule 1-3 times daily, as needed, or as recommended by a healthcare professional.
- Tru Niagen is intended for daily use. A 300mg serving has been clinically shown to increase NAD+ levels by over 50%.
- Depending on your lifestyle, stressors, and diet, an additional capsule of Tru Niagen may be considered.
- Tru Niagen has been shown to be safe for consumption at up to 2,000mg/day. Consult your healthcare provider before exceeding the recommended dosage.
- Niagen®, our patented nicotinamide riboside, increases NAD+ more efficiently than other NAD+ precursors.
- Nicotinamide riboside (NR) boosts NAD+ to support cellular function, energy production, and DNA repair.
- Supports cellular health, brain health and function, muscle health, and cardiovascular health.
- Supports healthy aging and those who experience active lifestyles, age-related concerns, and additional lifestyle stressors.
- Niagen® is one of the most well-researched, clinically studied NAD+ precursors available, routinely used in published peer-reviewed studies.
Niagen®
Our patented, safety-reviewed form of nicotinamide riboside (NR). One of the most well-researched, efficacious, and clinically proven NAD+ precursors available. Shown to easily pass through your cell walls, Niagen facilitates NAD+ production more efficiently than any other NAD+-boosting supplements or precursors.
Vegetarian
Free of gluten
Formulated without allergens
Safety-tested
Kosher
Halal
Tru Niagen® 300mg
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Our foundational daily serving of 300mg, known to boost and sustain NAD+ levels to over 50% in most individuals with daily use. Support your cellular energy production and support cellular repair with Niagen®, our award-winning, superior NAD+ precursor.
Tru Niagen is one of the most well-researched NAD+-boosting supplements available. Supports resilience against daily stressors and the natural aging process at the cellular level. Increase your NAD+ levels to support heart, brain, muscle, and whole-body health for enhanced vitality and healthy aging.
- Adults can take one capsule 1-3 times daily, as needed, or as recommended by a healthcare professional.
- Tru Niagen is intended for daily use. A 300mg serving has been clinically shown to increase NAD+ levels by over 50%.
- Depending on your lifestyle, stressors, and diet, an additional capsule of Tru Niagen may be considered.
- Tru Niagen has been shown to be safe for consumption at up to 2,000mg/day. Consult your healthcare provider before exceeding the recommended dosage.
- Niagen®, our patented nicotinamide riboside, increases NAD+ more efficiently than other NAD+ precursors.
- Nicotinamide riboside (NR) boosts NAD+ to support cellular function, energy production, and DNA repair.
- Supports cellular health, brain health and function, muscle health, and cardiovascular health.
- Supports healthy aging and those who experience active lifestyles, age-related concerns, and additional lifestyle stressors.
- Niagen® is one of the most well-researched, clinically studied NAD+ precursors available, routinely used in published peer-reviewed studies.
Niagen®
Our patented, safety-reviewed form of nicotinamide riboside (NR). One of the most well-researched, efficacious, and clinically proven NAD+ precursors available. Shown to easily pass through your cell walls, Niagen facilitates NAD+ production more efficiently than any other NAD+-boosting supplements or precursors.
Vegetarian
Free of gluten
Formulated without allergens
Safety-tested
Kosher
Halal
Whole-body benefits
From your daily routine to your biggest goals, Tru Niagen powers your cellular health, helping you thrive.
Increases blood NAD+ levels
NAD+ helps energy metabolism
NAD+ helps support biological function
NAD+ can support healthy tissue formation
Daily stressors can deplete NAD+. Replenish NAD+ to support your health.
Backed by gold standard science, quality, and safety
Efficacy backed by peer-reviewed published research
Partnership with 200+ institutions: We partner with top institutions like Mayo Clinic, National Institute on Aging, Harvard, and Cambridge.
Backed by independent research: 94% of Niagen® studies are independently peer-reviewed.
A clinical trial published in Nature Communications 2016
The study shows that nicotinamide riboside (NR) is orally bioavailable in mice and humans, increasing NAD+ levels and identifying NAAD as a key biomarker of increased NAD+ metabolism.
A clinical trial published in The American Journal of Clinical Nutrition in 2017
This study found that oral nicotinamide riboside (NR) increases blood NAD+ levels in healthy volunteers, suggesting potential therapeutic benefits for conditions involving mitochondrial dysfunction.
A clinical trial published in Nature Communications in 2018
Martens et al., 2018 This study found that nicotinamide riboside (NR) is safe, increases NAD+ levels, and may improve heart health by lowering blood pressure and arterial stiffness.
A clinical trial published in The American Journal of Clinical Nutrition in 2018
Dollerup et al., 2018 This study found that 12 weeks of nicotinamide riboside (NR) supplementation at 2000 mg/day is safe but does not improve insulin sensitivity or whole-body glucose metabolism in obese, insulin-resistant adults.
A clinical trial published in Nature Communications in 2019
Conze et al., 2019 This study found that long-term supplementation of nicotinamide riboside (NR) up to 1000 mg/day in healthy overweight adults is safe, well-tolerated, and dose-dependently increases blood NAD+ levels without affecting cholesterol levels.
A clinical trial published in The American Journal of Clinical Nutrition in 2019
Elhassan et al., 2019 This study found that nicotinamide riboside (NR) supplementation in aged humans increases the skeletal muscle NAD+ levels, downregulates energy metabolism pathways, and reduces circulating inflammatory cytokines, indicating anti-inflammatory effects without altering muscle mitochondrial bioenergetics.
A clinical trial published inThe American Journal of Clinical Nutrition in 2020
Remie et al., 2020 This study found that 6 weeks of nicotinamide riboside (NR) supplementation increased muscle NAD+ metabolites and fat-free mass in overweight or obese individuals, but had no effect on insulin sensitivity or mitochondrial function.
A clinical trial published in The Journal of Physiology in 2021
Stocks et al., 2021 This study found that 7 days of nicotinamide riboside (NR) supplementation did not affect whole-body metabolism, skeletal muscle mitochondrial function, or exercise-induced metabolic responses in humans, despite increasing certain NAD+ metabolites in muscle.
A clinical trial published in Science Advances in 2023
Lapatto et al., 2023 This study found that long-term nicotinamide riboside (NR) supplementation in BMI-discordant twins boosted NAD+ metabolism, increased muscle mitochondria and stem cell function, and improved gut bacteria.
A clinical trial published in the journal of Magnetic Resonance in Medicine in 2024
Nanga et al., 2024 This study found that acute supplementation of nicotinamide riboside (NR) significantly increased NAD+ levels in the human brain, as measured by downfield proton MRS, confirming NR's potential to boost cerebral NAD+ concentrations in healthy individuals.
Third-party verification for your health
Alkemist Assured™ Transparency Program
We partner with Alkemist Labs for the third-party testing of our products. Alkemist champions transparency, and provides their own consumer-friendly certificates of analysis on a regular basis as they continually test our products.
An Alkemist Assured seal confirms that Tru Niagen is verified and backed with potency and purity confirmation testing services for raw material and blended ingredient quality.
A minimum one year commitment is required for each product in the program in order to be permitted to use the Alkemist Assured™ seal.
Verified for Potency and Quality
We’ve built our reputation on quality, safety, and unmatched transparency. Tru Niagen® goes through extensive testing to ensure purity and potency, with each batch verified by leading third-party labs.
You can trust that every product meets the highest standards, and we make it easy for you to verify. Head to our Quality page to access your product’s certificate of analysis for full transparency on the quality you’re getting in every bottle.
Backed by 25 years of research & innovation
30+
Backed by peer-reviewed published studies.
2
Endorsed by a Scientific Advisory Board of world-leading researchers.
50+
Backed by innovation gold standards in the supplement space.
400+
NR is well-researched in published preclinical and clinical studies.
Frequently Asked Questions
NAD+ is vital for the cellular energy and repair that keeps you feeling your best. Low NAD+ levels mean your cells may struggle to stay energized and repair themselves.
NAD+ levels naturally decline from birth, accelerating around age 30, and dropping by up to 65% by age 70. Environmental and lifestyle stressors also diminish NAD+ levels, as do immune and health challenges. Tru Niagen® is clinically proven to significantly increase NAD+ levels, and help maintain them with daily use—to keep your body running smoothly as you age.
It's clinically proven that Tru Niagen 300mg increases NAD+ levels by over 50% with daily use, but it may take a few weeks to feel the effects though significant changes are happening at the cellular level. Stick with it, and you’ll experience better cellular energy, vitality, and overall health support.
Tru Niagen is a superior choice compared to other NAD supplements because it contains Niagen®, our patented nicotinamide riboside (NR), a more bioavailable precursor to NAD+. Niagen® NR crosses cell membranes easily and is efficiently converted into NAD+ inside cells, effectively boosting NAD+ levels.
This enhances energy metabolism, supports cellular repair, and promotes healthy aging, making Tru Niagen a more reliable and potent option for raising NAD+ compared to other supplements.
Subscribers enjoy exclusive savings, free shipping, and automatic delivery of Tru Niagen® every month. You’ll never run out, and you can cancel or adjust your subscription anytime. It’s the easiest way to ensure consistent NAD+ support for your daily health.