Sign up & subscribe: 30% off your first order, 10% off every order after + free shipping.

Sign up & subscribe: 30% off your first order, 10% off every order after + free shipping.

NEW: High-potency Tru Niagen 500mg. Upgrade your cellular health.

Your cart

View Cart

Your cart is empty

Continue shopping
A bottle of Tru Niagen supplement with 300mg dosage, featuring a blue label and white cap.
A bottle of Tru Niagen supplement with 300mg dosage, featuring a blue label and white cap. It also shows the blue carton packaging the bottle comes in.
A hand holding a Tru Nigen supplement on a blue background.
The Supplement Facts panel describing directions on how to use, which says "Adults take 1-3 capsules once daily". Each serving provides 263 mg of Niagen provided by 300 mg of Nicotinamide riboside chloride.
Tru Niagen® 300mg
TrustScore
Best Seller
A bottle of Tru Niagen supplement with 300mg dosage, featuring a blue label and white cap.

Our foundational daily serving of 300mg, clinically proven to increase and sustain blood NAD+ levels safely and effectively with daily use. Increasing NAD+ helps support your cellular energy production and cellular repair. Powered by our award-winning, superior NAD+ precursor, Niagen®.

Tru Niagen is one of the most well-researched NAD-boosting supplements available. Supports resilience against daily stressors and the natural aging process at the cellular level. Increase your NAD+ levels to support heart, brain, muscle, and whole-body health for enhanced vitality.

Made in the U.S. with globally sourced components.

Tru Niagen 300mg won the Consumer Choice Award, voted as a top supplement for those seeking a trusted solution for everyday wellness and cellular vitality.
Tru Niagen 300mg earned the prestigious "Most Beloved Brand" title in 2023, celebrating our trusted role in enhancing wellness through cellular health support.
Niagen was honored as the 2024 Healthy Aging Ingredient of the Year, underscoring our ingredient’s proven ability to promote long-term cellular resilience.
TESTED by SuppCo certified. Active ingredients independently verified by ISO 17025–accredited labs—anonymously purchased off the shelf, just like you would.

Tru Niagen® 300mg

The original—boost vital blood NAD+ levels with our minimum recommended daily serving. Get the details.

Select your capsule count:

Unlock 30% off your first order

Then 10% off every order after. Sign up here.

Free Shipping

Cancel Subscription Anytime

Subscribe & Save

Your price stays the same, whether you subscribe for a month or 6 months.

Note: Savings do not reflect promotional pricing.

Capsules 30 90 180
Monthly Cost $50.40 $135.20 $249.60
Price Per Serving $1.68 $1.50 $1.38
Savings $12.60 $33.80 $62.40
One-Time Purchase
Capsules 30 90 180
Monthly Cost $63.00 $169.00 $312.00
Price Per Serving $2.10 $1.88 $1.73
Savings $0 $0 $0

Our foundational daily serving of 300mg, clinically proven to increase and sustain blood NAD+ levels safely and effectively with daily use. Increasing NAD+ helps support your cellular energy production and cellular repair. Powered by our award-winning, superior NAD+ precursor, Niagen®.

Tru Niagen is one of the most well-researched NAD-boosting supplements available. Supports resilience against daily stressors and the natural aging process at the cellular level. Increase your NAD+ levels to support heart, brain, muscle, and whole-body health for enhanced vitality.

Made in the U.S. with globally sourced components.

Tru Niagen 300mg won the Consumer Choice Award, voted as a top supplement for those seeking a trusted solution for everyday wellness and cellular vitality.
Tru Niagen 300mg earned the prestigious "Most Beloved Brand" title in 2023, celebrating our trusted role in enhancing wellness through cellular health support.
Niagen was honored as the 2024 Healthy Aging Ingredient of the Year, underscoring our ingredient’s proven ability to promote long-term cellular resilience.
TESTED by SuppCo certified. Active ingredients independently verified by ISO 17025–accredited labs—anonymously purchased off the shelf, just like you would.

Backed by gold standard science and quality

Efficacy backed by peer-reviewed published research

Niagen® is supported by 45+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen®.**

Partnership with 200+ institutions: We partner with top institutions like Mayo Clinic, National Institute on Aging, Harvard, and Cambridge.

Backed by independent research: 94% of peer-reviewed, published Niagen® studies are investigator-driven and third-party funded.
View studies and publications
A clinical trial published in Nature Communications 2016

Trammell et al., 2016.

A clinical trial published in The American Journal of Clinical Nutrition in 2017

Airhart et al., 2017.

A clinical trial published in Nature Communications in 2018

Martens et al., 2018.

A clinical trial published in The American Journal of Clinical Nutrition in 2018

Dollerup et al., 2018.

A clinical trial published in Scientific Reports in 2019

Conze et al., 2019.

A clinical trial published in The American Journal of Clinical Nutrition in 2019

Elhassan et al., 2019.

A clinical trial published in The American Journal of Clinical Nutrition in 2020

Remie et al., 2020.

A clinical trial published in The Journal of Physiology in 2021

Stocks et al., 2021.

A clinical trial published in Science Advances in 2023

Lapatto et al., 2023.

A clinical trial published in Magnetic Resonance in Medicine in 2024

Nanga et al., 2024.

Hide studies and publications

Third-party verification for your health

We employ rigorous quality testing to support your health. Our science-backed supplements are routinely assessed by third-party testers for quality, safety, and potency.
Learn more
Alkemist Assured™ Transparency Program

We partner with Alkemist Labs for the third-party testing of our products. Alkemist champions transparency, and provides their own consumer-friendly certificates of analysis on a regular basis as they continually test our products.

An Alkemist Assured seal confirms that Tru Niagen is verified and backed with potency and purity confirmation testing services for raw material and blended ingredient quality.

A minimum one year commitment is required for each product in the program in order to be permitted to use the Alkemist Assured™ seal.

NSF Certified for Sport®

NSF’s Certified for Sport® is the only third-party certification recognized by United States Anti-Doping Agency (USADA), Major League Baseball (MLB), and the National Hockey League (NHL).

To earn this, supplements must meet strict quality standards, contain no unsafe contaminants, and be free of 270+ banned substances. Both Tru Niagen Stick Packs and Tru Niagen Pro are made in NSF-audited, GMP-certified facilities, with every batch verified for safety and transparency on NSF’s Certified for Sport® website.

Show less

Backed by 25+ years of research & innovation

From the NAD+ authority trusted by physicians, athletes, researchers, and a Nobel Prize-winning biochemist.

45+

Human Clinical Studies on Niagen® NR

60+

Proprietary NR Patents

500+

Published Scientific Studies

300+

Global Research Collaborations

Reviews

Overall rating: 4.3650794 / 5 from 63 reviews.

AI Generated Review Summary

Summary topics

Review topics: [].

Review highlights

Reviews

Tru Niagen 300

"I rely on a scientific proof of value I do not know yet if I have any changes but hope to see them in the future."

— Lina N. (5/5)

True Niagen

"Pleased with effect."

— Enid L. (4/5)

Hyped, but no relsults

"I toom for 3 months with no noticable benifits. Unfortuanly, i feel a little jipped, you know. i thought a 3 month go at it would give me something, but got nothing out of it."

— Ozzie O. (1/5)

Try Niagen

"Try Niagen"

— Michael C. (5/5)

Going good so far

"There aren’t any noticeable changes one month after starting. Might need more time."

— Joanna D. (4/5)

Fantastic Product

"I was prescribed the max dose of Tru Niagen by my functional medicine doctor. A comprehensive cellular analysis from Genova Labs showed what regular blood tests missed - I had critically low levels of B3 in my cells. Identifying nutritional deficiencies at a cellular level was a major piece of the puzzle in my recovery from chronic illness. After exhausting the traditional medicine system, I came up with no answers and no treatment. A holistic healing approach (mind, body, spirit, & soul) addressed the pillars of health and gave me back my life."

— Monica M. (5/5)

TruNiagen

"A young doctor recommended that I take TruNiagen daily as he had recommended his parents do as well. I’m a senior in my 80’s. I’m healthy, active and smart. I can’t say what I would be like without TruNiagen. I can’t say if TruNiagen has contributed to my wellbeing but I don’t wish to stop taking it and find out."

— Pat B. (5/5)

Clarity

"I would play chess on Wednesday nights after work and normally I would be tired and my brain was also tired. If however I took a Niagen vitamin in the morning none of this would happen. This is how I know it is different from other Vitamins because I could actually experience a difference. I will never stop taking it because I like to feel that way every day."

— Ted R. (5/5)

Hope

"Looking for general health improvement including brain health. Looking for a healthy lifestyle to continue on my journey of keeping healthy full of exercise. Hoping to supplement as to the quality of life"

— Brett M. (4/5)

I’m done

"Id like to cancel my subscription but no one will contact me to do that"

— Amy G. (5/5)

Q&A

Frequently Asked Questions

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

**Based on registered ongoing or completed clinical trials under "nicotinamide riboside" on clinicaltrials.gov.

***Based on revenue per largest U.S. e-commerce marketplace (Jan. 2025 – Dec. 2025)

†In combination with a healthy lifestyle.

‡In reference to physiological (not mental) stress.

§For use beyond 12 weeks, consult a health care professional.